California State University, Northridge WordmarkOviatt Library WordmarkOviatt Library Catalog Wordmark
Author Miller, Susan, 1955 December 21-
Title Handbook of flavoproteins [electronic resource] : Volume 1 oxidases, dehydrogenases and related systems.
Published Berlin : De Gruyter, 2013.
Book Cover
 Electronic Book  QP552.F54 H36 2013 v.1eb    ONLINE
Description 1 online resource : ill. (some col.)
Note Description based upon print version of record.
Contents Preface; 1 Berberine bridge enzyme and the family of bicovalent flavoenzymes; 1.1 Introduction; 1.2 The paradigm of bicovalent flavoenzymes: Berberine bridge enzyme (BBE) from Eschscholzia californica; 1.3 The family of BBE-like enzymes in the plant kingdom: how many and what for?; 1.4 The occurrence of BBE-like enzymes in fungi; 1.5 BBE-like enzymes in bacteria: oxidative power for the biosynthesis of antibiotics; 1.6 Conclusions; 1.7 Acknowledgments; 1.8 References; 2 PutA and proline metabolism; 2.1 Importance of proline metabolism; 2.2 Proline utilization A (PutA) proteins
2.3 Three-dimensional structures of PutA and PutA domains2.3.1 Structures of the catalytic domains of PutA; 2.3.2 Crystal structure of a minimalist PutA; 2.3.3 Solution structure of a trifunctional PutA and the role of the CTD; 2.4 Reaction kinetics of PutA; 2.4.1 Proline:ubiquinone oxidoreductase activity; 2.4.2 Substrate channeling; 2.5 DNA and membrane binding of trifunctional PutA; 2.5.1 DNA binding; 2.5.2 Membrane association; 2.6 PutA functional switching; 2.6.1 Redox-linked global conformational changes; 2.6.2 Local structural changes near the flavin
2.6.3 Residues important for functional switching2.7 Conclusions and future research directions; 2.8 Acknowledgements; 2.9 References; 3 Flavoenzymes involved in non-redox reactions; 3.1 Introduction; 3.2 Flavoenzymes for which flavin cofactors likely play redox-based catalytic roles; 3.2.1 Chorismate synthase; 3.2.2 4-Hydroxybutyryl-CoA dehydratase; 3.2.3 Polyunsaturated fatty acid isomerase; 3.2.4 4'-Phosphopantothenoylcysteine decarboxylase; 3.2.5 Other examples; 3.3 Flavoenzymes for which flavin cofactors likely play non-redox catalytic roles
3.3.1 Type 2 isopentenyl diphosphate isomerase3.3.2 UDP-galactopyranose mutase; 3.4 Flavoenzymes for which flavin cofactors play uncertain, but probably catalytic roles; 3.4.1 Lycopene cyclase; 3.4.2 Carotene cis-trans isomerase; 3.4.3 Fatty acid hydratase; 3.4.4 2-Haloacrylate hydratase; 3.5 Conclusions; 3.6 References; 4 Enzymes of FMN and FAD Metabolism; 4.1 Introduction; 4.2 Enzymes involved in the production of FMN and FAD in different organisms; 4.3 FMN and FAD metabolism in yeasts and mammals; 4.4 FMN and FAD metabolism in bacteria depends on a bifunctional enzyme
4.5 FMN and FAD metabolism in plants4.6 Conclusions and future research directions; 4.7 Acknowledgments; 4.8 References; 4.9 Abbreviations; 5 Mechanisms of bacterial luciferase and related flavin reductases; 5.1 Introduction; 5.2 Luciferase mechanism overview; 5.2.1 Mechanism of chemiexcitation; 5.2.2 Identity of primary excited state and emitter; 5.2.3 Multiple forms of 4a-hydroperoxy-FMNH intermediate II; 5.2.4 Aldehyde substrate inhibition; 5.3 Flavin reductases -- general remarks; 5.3.1 Mechanisms of flavin reductases in single-enzyme reactions
Note 5.3.2 Mechanisms of luciferase:flavin reductase coupled reactions
Summary The dynamic field of flavin and flavoprotein biochemistry has seen rapid advancement in recent years. Thisfirst book of thetwo volume set provides an overview of all aspects focussing on oxidases, dehydrogenases and related systems. Discussed arerecent developments in this field including those of large membrane-integral electron transfer complexes.It is an essential reference for all researchers in biochemistry, chemistry, photochemistry and photophysics working on flavoenzymes.
Subject Flavoproteins.
Related Names Gregersen, Niels Henrik, 1956-
Rokita, Steven Edward.
Becker, Donald.
Hille, Russ.
Palfey, Bruce.
Binda, Claudia.
Ceccarelli, Eduardo.
Chaiyen, Pimchai.
Costa Filho, Antonio J.
Daniel, Bastian.
Dully, Corinna.
Edmondson, D. E.
Fitzpatrick, Paul.
Gadda, Giovanni.
Ghisla, S. (Sandro), 1942-
Hemmi, Hisashi.
Jentoft Olsen, Rikke Katrine.
Kim, Ch┼Ćng-ja.
Macheroux, Peter.
Mattevi, Andrea.
Medina, M. (Milagros)
Nonato, Maria Cristina.
Schuman Jorns, Marilyn.
Tanner, John J.
Thorpe, Colin.
Tu, Shiao-Chun.
Vanoni, Maria A.
Wallner, Silvia.
Wongnate, Thanyaporn.
Related To Print version: Miller, Susan Handbook of Flavoproteins : Volume 1 Oxidases, Dehydrogenases and Related Systems Berlin : De Gruyter,c2012 9783110268423
ISBN 3110268914 (electronic bk.)
9783110268911 (electronic bk.)
OCLC number 829462145