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Title G protein coupled receptors : modeling, activation, interactions and virtual screening / edited by P. Michael Conn.
Published Amsterdam ; Boston : Academic Press/Elsevier, 2013
Book Cover

 Floor4  QP601 .M49 v.522 2013    IN LIBRARY
Edition First edition
Description lvi, 472 pages, 12 unnumbered pages of plates : illustrations (some color) ; 24 cm.
Content Type text
Format volume
Series Methods in enzymology, 0076-6879 ; v. 522
Methods in enzymology ; v. 522.
Bibliography Includes bibliographical references and indexes.
Contents The protein local optimization program and G-protein-coupled receptors : loop restoration and applications to homology modeling / Dahlia A. Goldfeld and Richard A. Friesner -- Modeling active GPCR conformations / Bruck Taddese, Lisa M. Simpson, Ian D. Wall, Frank E. Blaney, and Christopher A. Reynolds -- Molecular modeling of adenosine receptors / Adriano Martinelli and Gabriella Ortore -- Predicting G-protein-coupled receptors families using different physiochemical properties and pseudo amino acid composition / Zia-ur Rehman, Muhammad Tayyeb Mirza, Asifullah Khan, and Henri Xhaard -- Computational design and experimental characterization of GPCR segment models / Abby L. Parrill -- G-protein-coupled receptor interaction with small GTPases / Chunmin Dong and Guangyu Wu -- Quantification of receptor tyrosine kinase activiation and transactivation by G-protein-coupled receptors using spatial intensity distribution analysis (SplDA) / Annie Barbeau, Antoine G. Godin, Jody L. Swift, Yves De Koninck, Paul W. Wiseman, and Jean-Martin Beaulieu -- NMR modeling for detection of small molecule binding to RGS4 / Andrew J. Storaska and Richard R. Neubig --Group II activators of G-protein signaling : monitoring the interaction of G[alpha] with the G-protein regulatory motif in the intact cell / Sukru Sadik Oner, Joe B. Blumer, and Stephen M. Lanier -- Homogenous time-resolved fluorescence assay to probe folded G protein-coupled receptors / Adam M. Knepp, Thomas P. Sakmar, and Thomas Huber -- cAMP biosensors applied in molecular pharmacological studies of G protein-coupled receptors / Jesper Mosolff Mathiesen, Line Vedel, and Hans Bräuner-Osborne -- Rhodospin-lipid intereactions studied by NMR / Olivier Soubias and Klaus Gawrisch -- Biasing the parathyroid hormone receptor : relating in vitro ligand efficacy to in vivo biological activity / Kathryn M. Appleton, Mi-Hye Lee, Christian Alele, Christine Alele, Deirdre K. Luttrell, Yuri K. Peterson, Thomas A. Morinelli, and Louis M. Luttrell -- Application of Monte Carlo-based receptor ensemble docking to virtual screening for GPCR ligands / Santiago Vilar and Stefano Costanzi -- From heptahelical bundle to hits from the haystack : structure-based virtual screening for GPCR ligands / Albert J. Kooistra, Luc Roumen, Rob Leurs, Iwan J.P. de Esch, and Chris de Graaf -- Kinetics and dynamics in the G protein-coupled receptor signaling cascade / Jean-Pierre Vilardaga, Guillermo Romero, Timothy N. Feinstein, and Vanessa L. Wehbi -- Magic angle spinning nuclear magnetic resonance spectroscopy fo G protein-coupled receptors / Joseph Goncalves, Markus Eilers, Kieron South, Chikwado A. Opefi, Philippe Laissue, Philip J. Reeves, and Steven O. Smith -- Posttranslation modification of G protein-coupled receptor in relationship to biased agonism / Hui Zheng, Horace H. Loh, and Ping-Yee Law -- Protein S-nitrosylation measurement / Yu Qin, Anindya Dey, and Yehia Daaka.
Subject G proteins -- Receptors.
Nuclear magnetic resonance spectroscopy.
Related Names Conn, P. Michael.
ISBN 0124078656
OCLC number 827777632