California State University, Northridge WordmarkOviatt Library WordmarkOviatt Library Catalog Wordmark
Author Patel, Hiral, author.
Title Rapid translocation of DNA molecules through graphene nanogaps / by Hiral Patel.
Published [Northridge, California] : California State University, Northridge, 2012.
 Electronic Book  QC30 .Z95 2012 P38eb    ONLINE
Description 1 online resource (ix, 27 pages) : illustrations, color.
Content Type text
still image
Format online resource
File Characteristics text file PDF
Thesis M.S. California State University, Northridge 2012.
Bibliography Includes bibliographical references (pages 26-27).
Summary A nanogap is a small slit in a continuous impermeable membrane which may be used for active and passive transport of biological molecules. Biological nanopores and solid-state nanopores currently have limitations; however, graphene provides an ideal platform for biomolecule counting and characterization. Nanogaps fabricated in single layer graphene may give single base resolution that may enable DNA sequencing. Graphene flakes are produced by exfoliation and measured by close contact mode atomic force microscopy to determine the thickness of flakes and 150 nm deep, 2 æm wide trenches in SiO2 have been used to create a nanogap. The nanogap is measured in 0.1M KCl ionic solution, as individual DNA molecules translocate through the gap, characteristic conductance changes are observed in the ionic current through the nanogap. DNA translocation through several devices has been studied and it appears that the conductance blockade, [delta]G follows the same trend as graphene nanopore devices. In the context of graphene nanogaps, this thesis serves as a characterization of graphene nanogaps that is useful for future genome screening.
Note Description based on online resource; title from PDF title page (viewed on May 31, 2012).
Subject Graphene.
Nucleotide sequence.
Translocation (Genetics)
Local Subject Dissertations, Academic -- CSUN -- Physics and Astronomy.
OCLC number 847539601