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What is nitric oxide? / Nathan S. Bryan and Ferid Murad -- Mechanisms and physiological implications for nitric oxide insufficiency / Matthew B. Grisham and Nathan S. Bryan -- The nitrate-nitrite-nitric oxide pathway / Jon O. Lundberg and Eddie Weitzberg -- Dietary nitrates and nitrites : the physiological context for potential health benefits / Nathan S. Bryan and Norman G. Hord -- Nitrite and Nitrate in the meat industry / Randy Huffman and Nathan S. Bryan -- Physiological effects and mechanism of action of nitrite and nitrate in human physiology / Sruti Shiva and Mark T. Gladwin -- Polyphenols and flavanols as modulators of NO activity / Tienush Rassaf and Malte Kelm -- Nutritional epidemiology / Andrew L. Milkowski and James R. Coughlin -- Regulations gone awry : addressing public health concerns / Nathan S. Bryan and Norman G. Hord -- Diet and endothelium : two systems, redundant functions / Nathan S. Bryan and Norman G. Hord -- Nutrition and general health / Samuel Grief and Brazos Minshew -- Paradigm shift : from toxic food additive to indispensable nutrient / Nathan S. Bryan.